Enterobactin from Escherichia coli
Enterobactin
CAS: 28384-96-5
Molecular Formula: C30H27N3O15
Enterobactin from Escherichia coli - Names and Identifiers
| Name | Enterobactin |
| Synonyms | Enterobactin Enterobactin from Escherichia coli (3S,7S,11S)-3,7,11-Tris(2,3-dihydroxybenzoylamino)-1,5,9-trioxacyclododecane-2,6,10-trione N-(2,3-Dihydroxybenzoyl)cyclo[L-Ser*-N-(2,3-dihydroxybenzoyl)-L-Ser*-N-(2,3-dihydroxybenzoyl)-L-Ser*-] N,N',N''-((3S,7S,11S)-2,6,10-Trioxo-1,5,9-trioxacyclododecane-3,7,11-triyl)tris(2,3-dihydroxybenzamide) Benzamide, N,N',N''-[(3S,7S,11S)-2,6,10-trioxo-1,5,9-trioxacyclododecane-3,7,11-triyl]tris[2,3-dihydroxy- |
| CAS | 28384-96-5 |
Enterobactin from Escherichia coli - Physico-chemical Properties
| Molecular Formula | C30H27N3O15 |
| Molar Mass | 669.552 |
| Density | 1.72±0.1 g/cm3(Predicted) |
| Melting Point | 202-203° |
| Boling Point | 1109.1±65.0 °C(Predicted) |
| Specific Rotation(α) | D25 +7.40° (ethanol) |
| Solubility | Soluble in DMSO |
| pKa | 7.46±0.35(Predicted) |
| Storage Condition | -20°C |
Enterobactin from Escherichia coli - Introduction
General description Enterobactin synthesis occurs via nonribosomal peptide synthetases. The precursor chorismic acid is converted to intermediates isochorismate, 2,3-dihydro-2,3-dihydroxybenzoate and 2,3-dihydroxybenzoate (DHB). Final step involves the DHB and L-serine amide linkage. A total of six enzymes (ent AF) mediate enterobactin biosynthesis.This preparation of enterobactin is not bound to iron and will bind to Fe3 and Fe2 in solution. Biochemical/physiological effects Iron mobilization and take by microbes is mediated by low molecular weight complexing agents named siderophores. Enterobactin is a catechol (a benzenediol, C6H4(OH)2) type siderophore produced in small quantities by Escherichia coli and related enteric bacteria when grow on iron deficient media, and is one of the most powerful ferric ion complexing agents known. Enterobactin is a very effective sequestering agent for iron, can to remove iron from proteins, insoluble iron complexes, and other siderophores. Studies of the chemistry, regulation, synthesis, recognition, and transport of enterobactin make it the best-understood siderophore.
Last Update：2022-10-16 17:41:55
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View History
Enterobactin from Escherichia coli
N-(2-氨基乙基)-4-甲基苯磺酰胺
1-(6-氧代1H-吡啶-3-羰基)4-哌啶甲酸
SEVITERONEL (VT-464)
Benzene, [[(1R,2R)-1-fluoro-2-methoxypropyl]thio]-, rel- (9CI)
2-Thiophenecarboxamide, N-[1-[(2,4-dichlorophenyl)amino]-2-oxo-2-phenylethyl]-
DOTA-MONO-NHS-三叔丁酯
3-FORMYL-1H-INDOLE-2-CARBOXYLIC ACID
2,3,4,6-O-四乙酰基-beta-D-吡喃葡萄糖基异硫氰酸酯
3H-Oxazolo[3,2-a]oxireno[c]pyridine(9CI)
N-(2-氨基乙基)-4-甲基苯磺酰胺
1-(6-氧代1H-吡啶-3-羰基)4-哌啶甲酸
SEVITERONEL (VT-464)
Benzene, [[(1R,2R)-1-fluoro-2-methoxypropyl]thio]-, rel- (9CI)
2-Thiophenecarboxamide, N-[1-[(2,4-dichlorophenyl)amino]-2-oxo-2-phenylethyl]-
DOTA-MONO-NHS-三叔丁酯
3-FORMYL-1H-INDOLE-2-CARBOXYLIC ACID
2,3,4,6-O-四乙酰基-beta-D-吡喃葡萄糖基异硫氰酸酯
3H-Oxazolo[3,2-a]oxireno[c]pyridine(9CI)